Michigan Clinical Research Unit (MCRU)

MCRU Updates Cost Structure for Clinical Research Support Services

Due to recently announced changes in NIH financial support, MICHR’s Michigan Clinical Research Unit (MCRU) is updating its cost structure for both industry-sponsored and investigator-initiated research studies, effective July 1, 2015, in order to continue as a key clinical and translational research service provider:

New Industry-Sponsored Studies

Old Rate

New Rate

Protocol Administrative Life-Cycle (ALC) fee



Bundled MCRU service fee: 8 a.m. - 8 p.m.



Bundled MCRU service fee: 8 p.m. - 8 a.m.



MCRU2U services



Note: If these new rates will positively impact an existing study budget, PIs may
re-budget to the new fee structure as of July 1, 2015 upon notification of MCRU.

If there is no signed contract in place as of July 1, 2015, the new rates will be charged.

New Investigator-Initiated Studies

New Rate

Protocol Administrative Life-Cycle (ALC) fee


Bundled MCRU service fee: 8 a.m. - 8 p.m.


Bundled MCRU service fee: 8 p.m. - 8 a.m.


MCRU2U services


Laboratory services


MCRU space (CVC or Domino’s Farms)


Note: NIH, consortium, or foundation grant applications that are submitted before July 1, 2015, and then funded during this review cycle will not pay the new hourly rates until June 1, 2017.

All investigator-initiated existing studies (active/approved using MCRU now) will be subject to the new fee structure effective June 1, 2017, the commencement of the next five-year CTSA award cycle.

New studies being funded by PI discretionary or departmental resources that are approved by the IRB after July 1, 2015 will be subject to the new MCRU ALC fee and hourly rates.

MCRU staff is available to help research teams create or update budgets based on the new cost structure. If you have questions, please contact Dr. Blake Roessler at roessler@med.umich.edu or Cyndi Bower, Administrative Program Director, at bower@med.umich.edu.


The Michigan Clinical Research Unit (MCRU) provides the clinical staff, resources, and infrastructure necessary to conduct human clinical research protocols at the University of Michigan. MCRU hosts investigators funded by federal, state, and local agencies as well as those funded by the private sector. MCRU also serves as an institutional resource for investigators to perform pilot studies that may result in further agency funding.

Publishing Study Results: It is important that all publications resulting from studies conducted using the former GCRC & MCRU resources cite the CTSA grant number 2UL1TR000433-06. Studies using only the former GCRC resources should credit the GCRC: Grant #M01-RR000042. The NIH searches for publications by grant recognition, and our future resources will be tied to the number of publications referencing our grant number.

MCRU Facilities and Hours of Operation:

The main MCRU location is located in the Cardiovascular Center (CVC) on the medical campus. This is research space only with five overnight stay beds and five exam rooms that are used for outpatient and overnight research activities. This unit is open 8 a.m. - 8 p.m. and provides predictable opportunities for overnight stays and/or weekends.

We also have an outpatient site located in Lobby M at Domino's Farms and we provide service only to the Rachel Upjohn Building. Domino’s Farms operates Monday through Friday from 8 a.m. - 4:30 p.m. All of our sites are equipped to support adult and pediatric populations.

How to access MCRU:

MCRU is designed to serve as an infrastructural resource for clinical research investigators. To use MCRU, an investigator first needs to submit an application through the eResearch system. In order to utilize MCRU services, you will need to complete sections 1-2.4 and 42 in eResearch.

For a description of the MCRU resources for your grant proposal, click here. (64KB Word document)

The MCRU provides access to research nurses, medical assistants, and lab personnel. In addition, the main location houses the metabolic kitchen, specimen core and processing lab, and an exercise physiology room. See below for further details.

Mobile Clinical Research Team:

One of the valuable services provided by MICHR/MCRU is the access to our mobile research support team, MCRU2U. Our clinical staff provides integrated research support to clinical investigators and their study teams throughout the U-M campus and into the surrounding community. Our mobile team supports all specialized protocol specific services such as PK blood draws, ECGs etc. As part of this team we also provide access to a community-based research nurse and health worker to support study teams working with community outreach protocol specifics. The MCRU2U service is available from 8:00 to 4:00 Monday – Friday. 

Bionutrition Core: 

The bionutrition core is part of the Michigan Nutrition Obesity Research Center (MNORC). Nutrition assessment, counseling, body composition and metabolic kitchen services are available via NORC’s Nutrition Assessment Laboratory (NAL). MNORC NAL also offers investigators consultation services for study development and execution.

Please see the NORC website for further information.

Specimen Core and Processing Lab:

The MCRU has a specimen collection, processing, and shipping core laboratory that supports both overnight stay and outpatient clinical research for all of our performance sites. We have a sophisticated electronic specimen freezer management and inventory system. We provide short term-storage.

The MICHR Biorepository has been providing many, but not all, of the envisioned UMHS Biorepository services to the U-M research community for the last four years. Recently, the University of Michigan Medical School announced as part of its Strategic Research Plan the creation of a larger Central Biorepository to provide these services. The Central Biorepository (CBR) will be fully operational in late spring of 2015.  As a result, all new inquiries into long-term biospecimen storage and processing should be made of the CBR Director, Victoria Blanc, PhD.

Click here for more information http://medicine.umich.edu/medschool/research/office-research/biorepository

Contact Information: 
Victoria Blanc, Ph.D., Biorepository Director
UMMS Central Biorepository
2800 Plymouth Road, Building 36-1139, Ann Arbor, MI 48109-2800
 Office Phone: 734-763-6423

Meet the Crew of MCRU

MCRU Research Participant Scheduling Portal

The MCRU research participant scheduling portal was designed to facilitate research patient scheduling. Using the portal, investigators and study coordinators are able to submit their scheduling requests online to MCRU staff. MCRU staff is able to see all requests on a dashboard with all relevant information validated through online form submission. An automatic email is returned to acknowledge the scheduling request, and once the visit is approved by MCRU staff, an automatic email is created to confirm scheduling of the participant visit.

Go to MCRU Research Participant Scheduling Portal Application

For questions related to MCRU Scheduling, please contact MCRU scheduling 734.763.7363

To schedule a MCRU2U Just in Time Visit, please contact 734.936.8090


For general information about MCRU, please contact: 
Administrative Assistant Specialist 
LaTonya D. Berryhill, MBA, BBA
Cardiovascular Center Room 1702
1500 E. Medical Center Drive
Ann Arbor, MI 48109-5872
Phone: 734.936.8080 / e-mail ltweety@umich.edu 
Fax: 734.936.4024

MICHR Associate Director
Blake Roessler, MD

Professor of Internal Medicine

Administrative Program Director for the MICHR Clinical Research Support Group & MCRU Clinical Manager 
Cynthia L Bower, RN MS
Phone: 734.998.6885

Research Laboratory Supervisor
Gayle Carroll, BS 
Phone: 734.936.8082

Clinical Supervisor 
Jessica Virzi, RN
Phone: 734.232.5824

Bionutrition Core Manager

Theresa Han-Markey, MS, RD
Phone: 734.936.8075

Feedback on this page? E-mail LaTonya D. Payne



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