Clinical and translational research spans much of the research performed across the University of Michigan in areas related to human health. 

Clinical research is medical research that involves people like you. People volunteer to participate in carefully conducted investigations that ultimately uncover better ways to treat, prevent, diagnose, and understand human disease. Clinical research includes clinical trials that test new treatments and therapies as well as long-term natural history studies, which provide valuable information about how disease and health progress. 

Translational research is research that applies discoveries generated in the laboratory to studies in humans (bench to bedside), or that speeds the adoption of best practices into community settings (bedside to practice).

Phases of translational research include:

  • T1 – First phase of translational research, or “Bench to Bedside,” moves a basic discovery into a clinical application 
  • T2 – “Bedside to Practice” research provides evidence of the value of taking the basic discovery in the clinical setting 
  • T3 – Research that moves the evidence-based guidelines developed in phase 2 into health practice 
  • T4 – Research to evaluate the “real world” health outcomes of the original T1 development