Treatment Assignment Tool - University of Michigan (TATUM)


What is this service?

In a randomized clinical trial, the goal of treatment allocation is to assign patients to a treatment in an unbiased manner. In order to avoid bias it is important that neither the study participants nor the investigators know what the next treatment assignment is. One way that this masking of the assignment has traditionally been achieved is by sealing the treatment assignments in envelopes. When a researcher was ready to assign a study participant to a treatment, she would open the next envelope from the stack. It would contain the assigned treatment for the patient. This method is time-consuming and prone to occasional human error. It also does not facilitate central tracking of the randomizations.

The Treatment Assignment Tool - University of Michigan (TATUM) helps make treatment allocations for randomized studies fast and easy. The application replaces randomization envelopes, tracks progress of the study, and provides documentation of study treatment assignments. It is a secure, interactive web-based system used for centralized patient treatment assignment. The tool also provides a centralized location and process for multi-site studies to manage randomized subject treatment groups.

TATUM does not generate the randomization strategy. The lists, rules and questions must be produced by a qualified biostatistician and finalized before use in TATUM.

Who can use this service?

Principal investigators and study teams at U-M can use this service.

When should I contact MICHR about this service?

You should contact MICHR during the study design process.

How much does this service cost?

TATUM is free to studies sponsored by U-M. The cost pricing/recharge rates for this and other MICHR services are available here


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