WHAT IS CLINICAL & TRANSLATIONAL RESEARCH?

Clinical and translational research spans much of the research performed across the University of Michigan in areas related to human health. 

Clinical research is medical research that involves people like you. People volunteer to participate in carefully conducted investigations that ultimately uncover better ways to treat, prevent, diagnose, and understand human disease. Clinical research includes clinical trials that test new treatments and therapies as well as long-term natural history studies, which provide valuable information about how disease and health progress. 

Translational research is research that applies discoveries generated in the laboratory to studies in humans (bench to bedside), or that speeds the adoption of best practices into community settings (bedside to practice).

Phases of translational research include:

  • T1 – First stage of translational research, in which a foundational discovery or innovation is studied in healthy humans 
  • T2 – This next stage of research translates the finding from people to patients
  • T3 – This stage focuses on implementation of research findings in clinical practice 
  • T4 – After evaluating effects on practice, this stage of translation is focused on influencing populations and policy